PRKCSH

Across TCGA cell cohorts, PRKCSH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,143 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRKCSH-associated GO terms across cancer lineages are Multi-pass transmembrane protein insertion into ER membrane, Regulation of glycolytic process through fructose-6-phosphate, and Negative regulation of glycolytic process through fructose-6-phosphate. Each is linked with PRKCSH in more than 11 cancer types. Because this analysis shows association rather than direction, both PRKCSH-to-partner and partner-to-PRKCSH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multi-pass transmembrane protein insertion into ER membrane grouped by PRKCSH-low versus PRKCSH-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCSH→partner) and Y-score (partner→PRKCSH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Multi-pass transmembrane protein insertion into ER membrane →	+0.156	+0.907	.003	<.001	3	12
OVARY	Regulation of glycolytic process through fructose-6-phosphate →	+0.131	+0.754	<.001	<.001	3	11
OVARY	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.131	+0.754	<.001	<.001	3	11
BLOOD_Lymphoma	Protein localization to endoplasmic reticulum →	+0.092	+0.530	<.001	<.001	3	11
BLOOD_Lymphoma	Regulation of intracellular transport →	+0.048	+0.461	<.001	<.001	3	11
BLOOD_Myeloma	Glycolipid catabolic process →	+0.128	+0.568	.005	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,143 associations by consensus.

Multi-pass transmembrane protein insertion into ER membrane by PRKCSH expression — LIVER

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