PRKCI

Across TCGA patient cohorts, PRKCI RNA expression is significantly associated with the protein abundance of many other proteins, with 13,282 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRKCI-associated proteins across cancer lineages are GMPS, FXR1, and TBL1XR1. Each is linked with PRKCI in more than 7 cancer types. Because this analysis shows association rather than direction, both PRKCI-to-partner and partner-to-PRKCI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKCI versus GMPS in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCI→partner) and Y-score (partner→PRKCI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GMPS →	+0.469	+0.764	<.001	<.001	3	8
LSCC	FXR1 →	+0.478	+1.009	<.001	<.001	3	7
LSCC	TBL1XR1 →	+0.458	+0.710	<.001	<.001	3	6
LSCC	PCYT1A →	+0.556	+0.682	<.001	<.001	3	5
LSCC	U2SURP →	+0.224	+0.650	<.001	<.001	3	5
HNSC	DBR1 →	+0.242	+0.635	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,282 associations by consensus.

PRKCI vs GMPS — LSCC

Explore this scatter interactively →