PRKCI

Across TCGA cell cohorts, PRKCI RNA expression is significantly associated with the go_rna of many other GO terms, with 4,647 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRKCI-associated GO terms across cancer lineages are Golgi vesicle budding, Protein polyubiquitination, and Maintenance of centrosome location. Each is linked with PRKCI in more than 13 cancer types. Because this analysis shows association rather than direction, both PRKCI-to-partner and partner-to-PRKCI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle budding grouped by PRKCI-low versus PRKCI-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCI→partner) and Y-score (partner→PRKCI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Golgi vesicle budding →	+0.153	+0.896	<.001	<.001	3	14
BREAST	Protein polyubiquitination →	+0.027	+0.562	.002	<.001	3	11
OVARY	Maintenance of centrosome location →	+0.111	+0.848	<.001	.003	2	12
SKIN	Positive regulation of DNA recombination →	+0.057	+0.724	<.001	.002	3	11
LARGE_INTESTINE	Negative regulation of gene expression, epigenetic →	+0.042	+0.480	<.001	<.001	3	10
STOMACH	Vacuolar transport →	+0.060	+0.689	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,647 associations by consensus.

Golgi vesicle budding by PRKCI expression — STOMACH

Explore this box plot interactively →