PRKCD

Across TCGA pan-cancer cohorts, PRKCD mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PRKCD data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher PRKCD mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated PRKCD expression acts as an unfavorable survival marker.

CCRCC, PDAC, and COAD are the cancer types where PRKCD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	II,III,IV	0.596	0.937	.006	20	view →
PDAC	OS	Median	IV	0.381	0.951	.006	10	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
HNSC	DFS	Median	All	0.911	0.986	.003	5	view →
GBM	OS	Quartile	All	0.335	0.662	.013	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PRKCD–CCRCC (OS)

Open the CCRCC breakdown →