PRKCD

Across TCGA cell cohorts, PRKCD RNA expression is significantly associated with the go_rna of many other GO terms, with 5,318 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRKCD-associated GO terms across cancer lineages are Positive regulation of phospholipid catabolic process, Regulation of phospholipid catabolic process, and Negative regulation of actin filament polymerization. Each is linked with PRKCD in more than 19 cancer types. Because this analysis shows association rather than direction, both PRKCD-to-partner and partner-to-PRKCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of phospholipid catabolic process grouped by PRKCD-low versus PRKCD-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCD→partner) and Y-score (partner→PRKCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of phospholipid catabolic process →	+1.431	+1.299	<.001	<.001	3	20
PANCREAS	Regulation of phospholipid catabolic process →	+0.252	+1.301	<.001	<.001	3	15
URINARY_TRACT	Negative regulation of actin filament polymerization →	+0.185	+1.116	.001	.001	3	15
URINARY_TRACT	Negative regulation of protein polymerization →	+0.166	+1.235	.001	<.001	3	14
BONE	Intrinsic apoptotic signaling pathway in response to oxidative stress →	+0.149	+0.821	<.001	.004	3	12
OESOPHAGUS	Response to angiotensin →	+0.115	+0.987	.005	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,318 associations by consensus.

Positive regulation of phospholipid catabolic process by PRKCD expression — LUNG_SCLC

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