PRKCD

Across TCGA cell cohorts, PRKCD mutation is significantly associated with the mutation status of many other genes, with 5,857 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PRKCD-associated genes across cancer lineages are B4GALNT4, PRKD2, and GSE1. Each is linked with PRKCD in more than 4 cancer types. Because this analysis shows association rather than direction, both PRKCD-to-partner and partner-to-PRKCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B4GALNT4 grouped by PRKCD-low versus PRKCD-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCD→partner) and Y-score (partner→PRKCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	B4GALNT4 →	+2.155	+3.392	<.001	<.001	1	5
SKIN	PRKD2 →	+4.392	+4.392	.009	.009	1	4
BLOOD_Leukemia	GSE1 →	+2.975	+4.741	<.001	<.001	1	4
SKIN	NUMA1 →	+4.392	+4.392	.009	.009	1	4
BLOOD_Leukemia	IFT172 →	+3.560	+5.209	<.001	<.001	1	4
BLOOD_Leukemia	BAHD1 →	+4.560	+4.309	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,857 associations by consensus.

B4GALNT4 by PRKCD expression — LARGE_INTESTINE

Explore this box plot interactively →