PRKCB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRKCB protein abundance is significantly associated with the RNA expression of many other genes, with 19,261 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRKCB-associated genes across cancer lineages are FCER2, LILRA1, and EBI3. Each is linked with PRKCB in more than 8 cancer types. Because this analysis shows association rather than direction, both PRKCB-to-partner and partner-to-PRKCB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKCB versus FCER2 in LSCC, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCB→partner) and Y-score (partner→PRKCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCFCER2 →+0.697+0.631<.001<.00139
HNSCLILRA1 →+0.660+0.671<.001<.00139
BRCAEBI3 →+0.809+0.620<.001<.00139
LSCCBTK →+0.939+0.690<.001<.00139
BRCAPOU2AF1 →+1.456+0.848<.001<.00139
LSCCCD69 →+1.212+0.644<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,261 associations by consensus.

PRKCB vs FCER2 — LSCC

Per-sample scatter of PRKCB vs FCER2 in LSCC (Pearson r = 0.74).

Explore this scatter interactively →

Exploration