PRKCB

Across TCGA cell cohorts, PRKCB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,979 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRKCB-associated GO terms across cancer lineages are Positive regulation of mRNA metabolic process, Regulation of double-strand break repair, and Regulation of wound healing. Each is linked with PRKCB in more than 7 cancer types. Because this analysis shows association rather than direction, both PRKCB-to-partner and partner-to-PRKCB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mRNA metabolic process grouped by PRKCB-low versus PRKCB-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKCB→partner) and Y-score (partner→PRKCB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of mRNA metabolic process →	+0.041	+0.051	.002	.009	2	8
BONE	Regulation of double-strand break repair →	+0.064	+3.817	<.001	<.001	3	7
BONE	Regulation of wound healing →	-0.151	-4.938	<.001	<.001	3	6
BONE	Regulation of DNA recombination →	+0.077	+4.228	.003	<.001	3	6
BONE	Regulation of DNA repair →	+0.057	+3.821	<.001	<.001	3	6
BONE	RNA catabolic process →	+0.051	+4.400	.003	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,979 associations by consensus.

Positive regulation of mRNA metabolic process by PRKCB expression — PANCREAS

Explore this box plot interactively →