PRKAR2B

Across TCGA patient cohorts, PRKAR2B RNA expression is significantly associated with the protein abundance of many other proteins, with 15,471 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRKAR2B-associated proteins across cancer lineages are PRKAR2B_T69, PPP1R12B, and CLIC6. Each is linked with PRKAR2B in more than 7 cancer types. Because this analysis shows association rather than direction, both PRKAR2B-to-partner and partner-to-PRKAR2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAR2B versus PRKAR2B_T69 in HNSC, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAR2B→partner) and Y-score (partner→PRKAR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRKAR2B_T69 →	+1.230	+1.503	.001	<.001	3	8
UCEC	PPP1R12B →	+0.964	+0.700	<.001	<.001	3	6
BRCA	CLIC6 →	+1.154	+1.375	<.001	<.001	3	6
HNSC	ANK2 →	+0.588	+0.665	<.001	.002	3	5
UCEC	PGM5 →	+0.778	+0.677	<.001	<.001	3	5
UCEC	SPARCL1_S198 →	+1.423	+1.106	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,471 associations by consensus.

PRKAR2B vs PRKAR2B_T69 — HNSC

Explore this scatter interactively →