PRKAR2B

Across TCGA cell cohorts, PRKAR2B RNA expression is significantly associated with the RNA expression of many other genes, with 10,168 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRKAR2B-associated genes across cancer lineages are ZC3HC1, FAM184A, and SSX2IP. Each is linked with PRKAR2B in more than 6 cancer types. Because this analysis shows association rather than direction, both PRKAR2B-to-partner and partner-to-PRKAR2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAR2B versus ZC3HC1 in OVARY, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAR2B→partner) and Y-score (partner→PRKAR2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ZC3HC1 →	+0.732	+1.431	<.001	<.001	3	7
LARGE_INTESTINE	FAM184A →	+1.287	+1.269	<.001	<.001	3	6
BLOOD_Lymphoma	SSX2IP →	+1.126	+2.949	<.001	<.001	3	6
LUNG_NSCLC_LUSC	RHOQ →	+1.626	+2.106	<.001	<.001	3	6
BLOOD_Leukemia	MOB1B →	+1.013	+1.610	<.001	<.001	3	6
LUNG_SCLC	BRSK1 →	+1.937	+1.653	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,168 associations by consensus.

PRKAR2B vs ZC3HC1 — OVARY

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