Across TCGA patient cohorts, PRKAR1B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,004 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKAR1B-associated proteins across cancer lineages are FOXK1, FKBP11, and NUCB2. Each is linked with PRKAR1B in more than 5 cancer types. Because this analysis shows association rather than direction, both PRKAR1B-to-partner and partner-to-PRKAR1B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAR1B→partner) and Y-score (partner→PRKAR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FOXK1 →	+0.365	+0.651	.002	.004	3	6
GBM	FKBP11 →	-0.686	-1.086	<.001	<.001	3	4
LUAD	NUCB2 →	-0.506	-0.703	<.001	<.001	3	4
COAD	ARFGAP3 →	-0.301	-0.701	<.001	<.001	3	4
BRCA	TBC1D17 →	-0.309	-0.501	.001	.007	3	4
LSCC	DNAJC1 →	-0.524	-0.743	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,004 associations by consensus.

Exploration

PRKAR1B survival (RNA) · tumor vs normal (RNA) · all PRKAR1B data types