Across TCGA patient cohorts, PRKAR1B protein abundance is significantly associated with the RNA expression of many other genes, with 9,675 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKAR1B-associated genes across cancer lineages are SMIM10L2A, FAM124A, and FAM20A. Each is linked with PRKAR1B in more than 3 cancer types. Because this analysis shows association rather than direction, both PRKAR1B-to-partner and partner-to-PRKAR1B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAR1B→partner) and Y-score (partner→PRKAR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMIM10L2A →	+0.758	+0.467	<.001	<.001	3	4
GBM	FAM124A →	+0.726	+0.588	<.001	<.001	3	4
OV	FAM20A →	-1.694	-0.524	<.001	<.001	3	3
GBM	PLAU →	-1.501	-0.533	<.001	<.001	3	3
OV	PIN1 →	+0.850	+0.401	<.001	.003	3	3
OV	CXCL1 →	-1.935	-0.541	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,675 associations by consensus.

Exploration

PRKAR1B survival (RNA) · tumor vs normal (RNA) · all PRKAR1B data types