Across TCGA cell cohorts, PRKAR1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,399 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRKAR1B-associated GO terms across cancer lineages are Activation of protein kinase A activity, Positive regulation of fear response, and Vascular endothelial cell response to fluid shear stress. Each is linked with PRKAR1B in more than 17 cancer types. Because this analysis shows association rather than direction, both PRKAR1B-to-partner and partner-to-PRKAR1B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAR1B→partner) and Y-score (partner→PRKAR1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Activation of protein kinase A activity →	+0.257	+2.148	<.001	<.001	3	18
URINARY_TRACT	Positive regulation of fear response →	+1.295	+1.333	<.001	.002	3	16
PANCREAS	Vascular endothelial cell response to fluid shear stress →	+0.108	+1.573	<.001	<.001	3	13
PANCREAS	Vascular endothelial cell response to laminar fluid shear stress →	+0.139	+1.459	<.001	<.001	3	13
PANCREAS	Cellular response to glucagon stimulus →	+0.132	+1.108	<.001	<.001	3	13
LIVER	Response to glucagon →	+0.155	+1.865	.002	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,399 associations by consensus.

Exploration

PRKAR1B survival (RNA) · tumor vs normal (RNA) · all PRKAR1B data types