PRKAG1

Across TCGA patient cohorts, PRKAG1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,116 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRKAG1-associated genes across cancer lineages are PRKAB1, NDC80, and VRK1. Each is linked with PRKAG1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRKAG1-to-partner and partner-to-PRKAG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAG1 versus PRKAB1 in LUAD, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAG1→partner) and Y-score (partner→PRKAG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRKAB1 →	+0.685	+0.184	<.001	<.001	3	7
GBM	NDC80 →	-1.131	-0.220	<.001	<.001	3	6
COAD	VRK1 →	-0.591	-0.213	.002	.002	3	5
UCEC	SGO1 →	-0.730	-0.185	.001	.006	3	5
LUAD	BRIP1 →	-0.777	-0.263	<.001	<.001	3	5
UCEC	KIF15 →	-0.962	-0.279	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,116 associations by consensus.

PRKAG1 vs PRKAB1 — LUAD

Explore this scatter interactively →