PRKAB1

Across TCGA patient cohorts, PRKAB1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,798 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRKAB1-associated genes across cancer lineages are TNFAIP6, FCGR2A, and ANKDD1B. Each is linked with PRKAB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRKAB1-to-partner and partner-to-PRKAB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAB1 versus TNFAIP6 in COAD, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAB1→partner) and Y-score (partner→PRKAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TNFAIP6 →	-1.158	-0.311	<.001	<.001	3	5
COAD	FCGR2A →	-0.706	-0.307	<.001	<.001	3	5
LUAD	ANKDD1B →	+0.947	+0.279	<.001	<.001	3	5
COAD	NDC80 →	-0.906	-0.437	<.001	.001	3	5
BRCA	ARL1 →	+0.500	+0.213	<.001	<.001	3	4
COAD	SPHK1 →	-0.945	-0.328	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,798 associations by consensus.

PRKAB1 vs TNFAIP6 — COAD

Explore this scatter interactively →