PRKAB1

Across TCGA cell cohorts, PRKAB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,392 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRKAB1-associated GO terms across cancer lineages are Phospholipid biosynthetic process, Glycerophospholipid biosynthetic process, and Vacuolar transport. Each is linked with PRKAB1 in more than 12 cancer types. Because this analysis shows association rather than direction, both PRKAB1-to-partner and partner-to-PRKAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phospholipid biosynthetic process grouped by PRKAB1-low versus PRKAB1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAB1→partner) and Y-score (partner→PRKAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Phospholipid biosynthetic process →	+0.036	+0.774	<.001	<.001	3	13
STOMACH	Glycerophospholipid biosynthetic process →	+0.038	+0.999	.001	.001	2	12
BLOOD_Myeloma	Vacuolar transport →	+0.057	+0.951	<.001	<.001	3	10
BLOOD_Myeloma	Macroautophagy →	+0.061	+0.831	<.001	<.001	3	10
LUNG_SCLC	Sperm motility →	-0.089	-0.831	.007	<.001	3	10
BLOOD_Myeloma	Regulation of organelle assembly →	+0.036	+0.667	.001	.004	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,392 associations by consensus.

Phospholipid biosynthetic process by PRKAB1 expression — BREAST

Explore this box plot interactively →