PRKAA2

Across TCGA patient cohorts, PRKAA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,524 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PRKAA2-associated proteins across cancer lineages are PRKAA2_S377, PRKAA2_S491, and PYCARD. Each is linked with PRKAA2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PRKAA2-to-partner and partner-to-PRKAA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAA2 versus PRKAA2_S377 in BRCA, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAA2→partner) and Y-score (partner→PRKAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PRKAA2_S377 →	+1.031	+1.745	<.001	<.001	3	10
HNSC	PRKAA2_S491 →	+1.873	+1.684	<.001	<.001	3	10
CCRCC	PYCARD →	-0.447	-0.518	<.001	<.001	3	5
LSCC	PTBP2 →	+0.869	+0.899	<.001	<.001	3	5
GBM	CASP4 →	-0.634	-0.788	<.001	<.001	3	5
CCRCC	CARD9_S460 →	-0.663	-1.028	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,524 associations by consensus.

PRKAA2 vs PRKAA2_S377 — BRCA

Explore this scatter interactively →