PRKAA2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRKAA2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,251 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRKAA2-associated genes across cancer lineages are TTLL7, NBEA, and C1orf115. Each is linked with PRKAA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRKAA2-to-partner and partner-to-PRKAA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRKAA2 versus TTLL7 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRKAA2→partner) and Y-score (partner→PRKAA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCTTLL7 →+0.937+0.479<.001.00136
LSCCNBEA →+0.797+0.471.001<.00135
CCRCCC1orf115 →+0.971+0.403<.001<.00135
BRCAFYB2 →+1.348+0.792<.001<.00134
GBMATPAF1 →+0.356+0.319<.001.00134
BRCAMOAP1 →+0.576+0.623<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,251 associations by consensus.

PRKAA2 vs TTLL7 — LSCC

Per-sample scatter of PRKAA2 vs TTLL7 in LSCC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration