Across TCGA patient cohorts, PRIM1 mutation is significantly associated with the RNA expression of many other genes, with 236 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRIM1-associated genes across cancer lineages are RN7SL131P, MIR3910-1, and FAM177A1. Each is linked with PRIM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRIM1-to-partner and partner-to-PRIM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRIM1→partner) and Y-score (partner→PRIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SL131P →	+0.199	+3.748	<.001	.008	3	2
LUSC	MIR3910-1 →	+0.375	+6.008	<.001	<.001	3	2
UCEC	FAM177A1 →	+0.475	+3.595	.002	.001	3	1
UCEC	RPP14 →	+0.436	+3.330	.003	.005	3	1
UCEC	MS4A5 →	+0.090	+2.427	.008	.006	3	1
UCEC	ZNF274 →	+0.578	+3.595	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

Exploration

PRIM1 survival (RNA) · tumor vs normal (RNA) · all PRIM1 data types