Across TCGA patient cohorts, PRIM1 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRIM1-associated genes across cancer lineages are CD8+ T-cells, pDC, and CD8+ Tcm. Each is linked with PRIM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRIM1-to-partner and partner-to-PRIM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRIM1→partner) and Y-score (partner→PRIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ T-cells →	+0.017	+2.108	.003	.046	3	2
UCEC	pDC →	+0.051	+3.177	.029	.010	3	2
UCEC	CD8+ Tcm →	+0.018	+2.765	.049	.005	3	1
UCEC	CD8+ Tem →	+0.003	+4.481	<.001	.047	3	1
UCEC	cDC →	+0.095	+2.818	.015	.035	3	1
UCEC	DC →	+0.022	+2.518	.022	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

PRIM1 survival (RNA) · tumor vs normal (RNA) · all PRIM1 data types