PRH2

Across TCGA patient cohorts, PRH2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,219 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PRH2-associated genes across cancer lineages are DMC1, BMX, and CAB39L. Each is linked with PRH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRH2-to-partner and partner-to-PRH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRH2 versus DMC1 in HNSC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRH2→partner) and Y-score (partner→PRH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DMC1 →	-0.732	-2.261	.001	<.001	3	1
HNSC	BMX →	+0.634	+1.939	<.001	.001	3	1
HNSC	CAB39L →	+0.717	+1.671	.003	.009	3	1
HNSC	GIPR →	+0.587	+1.826	<.001	.002	3	1
HNSC	DENND3 →	+0.685	+1.626	<.001	.004	3	1
HNSC	PBX4 →	+0.508	+1.514	.009	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,219 associations by consensus.

PRH2 vs DMC1 — HNSC

Explore this scatter interactively →