PRH2

Across TCGA cell cohorts, PRH2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PRH2-associated genes across cancer lineages are GUCA1C and OR4D2. Each is linked with PRH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRH2-to-partner and partner-to-PRH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCA1C grouped by PRH2-low versus PRH2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRH2→partner) and Y-score (partner→PRH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	GUCA1C →	+0.115	+5.228	<.001	.005	3	1
LUNG_SCLC	OR4D2 →	+0.022	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

GUCA1C by PRH2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →