Across TCGA patient cohorts, PRG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,053 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible PRG2-associated GO terms across cancer lineages are Negative regulation of kinase activity, Cellular response to oxidative stress, and Glycerophospholipid metabolic process. Each is linked with PRG2 in more than 20 cancer types. Because this analysis shows association rather than direction, both PRG2-to-partner and partner-to-PRG2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRG2→partner) and Y-score (partner→PRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Negative regulation of kinase activity →	+0.056	+0.132	<.001	<.001	3	21
ESCA	Cellular response to oxidative stress →	+0.032	+0.108	.003	<.001	3	21
ESCA	Glycerophospholipid metabolic process →	+0.044	+0.143	<.001	<.001	3	21
ESCA	Protein folding →	+0.039	+0.100	.002	<.001	3	20
ESCA	Negative regulation of transferase activity →	+0.054	+0.130	.001	<.001	3	20
UVM	Glycerophospholipid biosynthetic process →	+0.041	+0.249	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,053 associations by consensus.

Exploration

PRG2 survival (RNA) · tumor vs normal (RNA) · all PRG2 data types