Across TCGA patient cohorts, PRG2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,477 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRG2-associated genes across cancer lineages are CLC, CLEC10A, and CCL11. Each is linked with PRG2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRG2-to-partner and partner-to-PRG2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRG2→partner) and Y-score (partner→PRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CLC →	+1.943	+0.984	<.001	<.001	3	8
OV	CLEC10A →	+1.321	+0.848	<.001	<.001	3	7
OV	CCL11 →	+1.893	+0.951	<.001	<.001	3	7
GBM	FCN1 →	+1.086	+0.861	<.001	<.001	3	7
GBM	ADGRE3 →	+0.735	+0.560	<.001	<.001	3	6
GBM	JAML →	+1.035	+0.590	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,477 associations by consensus.

Exploration

PRG2 survival (RNA) · tumor vs normal (RNA) · all PRG2 data types