PREPL

Across TCGA patient cohorts, PREPL RNA expression is significantly associated with the protein abundance of many other proteins, with 22,164 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PREPL-associated proteins across cancer lineages are PTPRC, RCOR3, and SPCS3. Each is linked with PREPL in more than 5 cancer types. Because this analysis shows association rather than direction, both PREPL-to-partner and partner-to-PREPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PREPL versus PTPRC in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PREPL→partner) and Y-score (partner→PREPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTPRC →	-0.707	-0.442	<.001	<.001	3	6
HNSC	RCOR3 →	+0.421	+0.690	<.001	<.001	3	5
LSCC	SPCS3 →	-0.458	-0.425	<.001	<.001	3	5
BRCA	TCEAL4 →	+0.443	+0.395	<.001	.002	3	5
CCRCC	TMED9 →	-0.330	-0.401	.003	.002	3	5
HNSC	VEZF1 →	+0.387	+0.469	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,164 associations by consensus.

PREPL vs PTPRC — GBM

Explore this scatter interactively →