PREPL

Across TCGA cell cohorts, PREPL RNA expression is significantly associated with the RNA expression of many other genes, with 10,497 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible PREPL-associated genes across cancer lineages are SPAST, THAP6, and CAMKMT. Each is linked with PREPL in more than 16 cancer types. Because this analysis shows association rather than direction, both PREPL-to-partner and partner-to-PREPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PREPL versus SPAST in OESOPHAGUS, with a Pearson correlation of 0.70.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PREPL→partner) and Y-score (partner→PREPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	SPAST →	+1.098	+1.073	<.001	<.001	3	17
BLOOD_Lymphoma	THAP6 →	+0.866	+1.259	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	CAMKMT →	+1.224	+1.472	<.001	<.001	3	15
OESOPHAGUS	HEATR5B →	+1.182	+1.108	<.001	<.001	2	16
LUNG_NSCLC_LUSC	PIKFYVE →	+1.327	+0.914	<.001	<.001	2	16
BLOOD_Myeloma	SOS1 →	+0.979	+0.748	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,497 associations by consensus.

PREPL vs SPAST — OESOPHAGUS

Explore this scatter interactively →