PREPL

Across TCGA cell cohorts, PREPL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,378 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible PREPL-associated GO terms across cancer lineages are Microtubule-based transport, Transport along microtubule, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with PREPL in more than 13 cancer types. Because this analysis shows association rather than direction, both PREPL-to-partner and partner-to-PREPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based transport grouped by PREPL-low versus PREPL-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PREPL→partner) and Y-score (partner→PREPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Microtubule-based transport →	+0.053	+1.162	.002	<.001	3	14
CNS	Transport along microtubule →	+0.046	+0.649	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, cytochrome c to oxygen →	+0.114	+1.143	<.001	<.001	3	14
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.060	+0.481	.003	.002	2	14
STOMACH	Regulation of organelle assembly →	+0.062	+0.753	.004	.003	3	12
STOMACH	Non-motile cilium assembly →	+0.055	+0.691	.001	.005	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,378 associations by consensus.

Microtubule-based transport by PREPL expression — LIVER

Explore this box plot interactively →