PREP

Across TCGA cell cohorts, PREP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,018 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PREP-associated GO terms across cancer lineages are Regulation of angiotensin levels in blood, Angiotensin maturation, and Hair follicle placode formation. Each is linked with PREP in more than 13 cancer types. Because this analysis shows association rather than direction, both PREP-to-partner and partner-to-PREP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of angiotensin levels in blood grouped by PREP-low versus PREP-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PREP→partner) and Y-score (partner→PREP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of angiotensin levels in blood →	+0.224	+0.664	.006	.001	3	14
SOFT_TISSUE	Angiotensin maturation →	+0.224	+0.664	.006	.001	3	14
BLOOD_Myeloma	Hair follicle placode formation →	+0.072	+0.691	.003	<.001	3	12
BLOOD_Leukemia	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.082	+0.519	<.001	<.001	3	9
OVARY	7-methylguanosine mRNA capping →	+0.121	+0.978	<.001	<.001	3	9
OVARY	7-methylguanosine RNA capping →	+0.121	+0.978	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,018 associations by consensus.

Regulation of angiotensin levels in blood by PREP expression — SOFT_TISSUE

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