PRELID3B

Across TCGA patient cohorts, PRELID3B mutation is significantly associated with the RNA expression of many other genes, with 363 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRELID3B-associated genes across cancer lineages are MIR6515, SNORA36C, and MIR4744. Each is linked with PRELID3B in more than 1 cancer types. Because this analysis shows association rather than direction, both PRELID3B-to-partner and partner-to-PRELID3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6515 grouped by PRELID3B-low versus PRELID3B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRELID3B→partner) and Y-score (partner→PRELID3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR6515 →	+0.476	+7.640	<.001	.009	3	2
UCEC	SNORA36C →	+0.232	+3.136	<.001	.007	3	2
UCEC	MIR4744 →	+0.434	+2.600	.003	.005	3	1
UCEC	RN7SL147P →	+0.212	+2.550	.001	.006	3	1
UCEC	MIR548AI →	+0.258	+4.566	<.001	.003	3	1
UCEC	MIR4782 →	+0.558	+3.068	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 363 associations by consensus.

MIR6515 by PRELID3B expression — BLCA

Explore this box plot interactively →