PRELID3B

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PRELID3B mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRELID3B-associated genes across cancer lineages are Mesangial cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with PRELID3B in more than 1 cancer types. Because this analysis shows association rather than direction, both PRELID3B-to-partner and partner-to-PRELID3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mesangial cells grouped by PRELID3B-low versus PRELID3B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRELID3B→partner) and Y-score (partner→PRELID3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMesangial cells →-0.068-3.311<.001.01031
UCECEndothelial cells →-0.056-3.279.005.01111
UCEClymphatic Endothelial cells →-0.032-3.268.011.01111
UCECmv Endothelial cells →-0.033-3.311.008.01011
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Mesangial cells by PRELID3B expression — UCEC

Box plot of Mesangial cells in PRELID3B-low vs PRELID3B-high samples in UCEC.

Explore this box plot interactively →

Exploration