Across TCGA patient cohorts, PRELID2 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRELID2-associated genes across cancer lineages are EGFR_pY1068, JNK_pT183_Y185, and Myosin-IIa. Each is linked with PRELID2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRELID2-to-partner and partner-to-PRELID2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRELID2→partner) and Y-score (partner→PRELID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.298	-3.321	.023	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.275	-3.308	.001	.010	3	1
UCEC	Myosin-IIa →	+0.204	+2.177	.036	.035	3	1
UCEC	Rab25 →	-0.736	-3.321	<.001	.010	3	1
UCEC	Rictor_pT1135 →	-0.158	-3.321	.003	.010	3	1
UCEC	VHL →	-1.351	-3.321	<.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

PRELID2 survival (RNA) · tumor vs normal (RNA) · all PRELID2 data types