PRDX6

Across TCGA patient cohorts, PRDX6 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,292 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRDX6-associated proteins across cancer lineages are CACYBP, DHX9, and PRDX6_T44. Each is linked with PRDX6 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRDX6-to-partner and partner-to-PRDX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDX6 versus CACYBP in LSCC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX6→partner) and Y-score (partner→PRDX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CACYBP →	+0.403	+0.646	<.001	<.001	3	7
LSCC	DHX9 →	+0.320	+0.682	<.001	<.001	3	7
LSCC	PRDX6_T44 →	+0.677	+0.723	<.001	<.001	3	7
UCEC	RPRD2 →	+0.315	+0.706	<.001	<.001	3	6
LSCC	TRMT1L →	+0.384	+0.454	<.001	<.001	3	6
UCEC	IPO9 →	+0.370	+0.815	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,292 associations by consensus.

PRDX6 vs CACYBP — LSCC

Explore this scatter interactively →