PRDX4P1

Across TCGA patient cohorts, PRDX4P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,185 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PRDX4P1-associated GO terms across cancer lineages are Positive regulation of transporter activity, Positive regulation of transmembrane transport, and Negative regulation of RNA splicing. Each is linked with PRDX4P1 in more than 4 cancer types. Because this analysis shows association rather than direction, both PRDX4P1-to-partner and partner-to-PRDX4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transporter activity grouped by PRDX4P1-low versus PRDX4P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX4P1→partner) and Y-score (partner→PRDX4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of transporter activity →	+0.079	+0.064	<.001	<.001	2	5
ESCA	Positive regulation of transmembrane transport →	+0.103	+0.048	<.001	.007	2	5
STAD	Negative regulation of RNA splicing →	+0.174	+0.036	<.001	<.001	3	4
STAD	Negative regulation of mRNA processing →	+0.162	+0.048	<.001	<.001	3	4
STAD	Pyrimidine nucleotide metabolic process →	+0.127	+0.048	<.001	<.001	3	4
STAD	Regulation of stress-activated protein kinase signaling cascade →	+0.124	+0.030	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,185 associations by consensus.

Positive regulation of transporter activity by PRDX4P1 expression — STAD

Explore this box plot interactively →