PRDX3P3

Across TCGA pan-cancer cohorts, PRDX3P3 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated PRDX3P3 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PRDX3P3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PRDX3P3 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

COAD, PAAD, and THCA are the cancer types where PRDX3P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	II,III,IV	0.393	0.854	<.001	81	view →
PAAD	DFS	Tertile	All	0.261	0.495	.006	45	view →
THCA	DFS	Tertile	IV	0.075	0.807	<.001	39	view →
LGG	OS	Tertile	All	0.598	0.832	<.001	36	view →
ACC	OS	Tertile	All	0.248	0.831	<.001	36	view →
UCEC	OS	Tertile	III,IV	0.646	0.835	.018	36	view →
SKCM	OS	Tertile	III,IV	1.000	0.666	.016	21	view →
ESCA	OS	Tertile	All	0.359	0.560	.020	18	view →
LUSC	OS	Tertile	III,IV	0.122	0.673	<.001	18	view →
PCPG	DFS	Tertile	All	0.070	0.936	<.001	18	view →
OV	DFS	Tertile	III,IV	0.225	0.375	.027	12	view →
KICH	OS	Tertile	All	0.831	0.992	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

PRDX3P3–COAD (OS)

Open the COAD breakdown →