PRDX2

Across TCGA cell cohorts, PRDX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,174 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRDX2-associated GO terms across cancer lineages are Cell cycle phase transition, Regulation of G2/MI transition of meiotic cell cycle, and DNA strand elongation involved in DNA replication. Each is linked with PRDX2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRDX2-to-partner and partner-to-PRDX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell cycle phase transition grouped by PRDX2-low versus PRDX2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX2→partner) and Y-score (partner→PRDX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cell cycle phase transition →	+0.081	+3.000	.005	.001	3	9
BONE	Regulation of G2/MI transition of meiotic cell cycle →	+0.135	+3.450	.002	.003	3	8
BONE	DNA strand elongation involved in DNA replication →	+0.190	+2.968	<.001	.002	3	8
SOFT_TISSUE	Wound healing →	-0.116	-1.568	<.001	.006	3	8
UPPER_AERODIGESTIVE_TRACT	Hydrogen peroxide catabolic process →	+0.096	+1.142	.002	.001	3	8
LUNG_SCLC	Regulation of glucose mediated signaling pathway →	+0.187	+2.586	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,174 associations by consensus.

Cell cycle phase transition by PRDX2 expression — BONE

Explore this box plot interactively →