PRDX1

Across TCGA patient cohorts, PRDX1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRDX1-associated genes across cancer lineages are Adipocytes, CD8+ Tem, and Pericytes. Each is linked with PRDX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRDX1-to-partner and partner-to-PRDX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by PRDX1-low versus PRDX1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX1→partner) and Y-score (partner→PRDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.026	+3.244	.025	.020	3	2
UCEC	CD8+ Tem →	+0.006	+5.481	<.001	.025	3	1
UCEC	Pericytes →	+0.037	+2.528	.034	.025	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Adipocytes by PRDX1 expression — UCEC

Explore this box plot interactively →