PRDX1

Across TCGA cell cohorts, PRDX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,153 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRDX1-associated GO terms across cancer lineages are Response to thyroxine, Somatic cell DNA recombination, and Somatic diversification of immune receptors via germline recombination within a single locus. Each is linked with PRDX1 in more than 10 cancer types. Because this analysis shows association rather than direction, both PRDX1-to-partner and partner-to-PRDX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to thyroxine grouped by PRDX1-low versus PRDX1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX1→partner) and Y-score (partner→PRDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Response to thyroxine →	+0.157	+0.719	.004	.003	3	11
SKIN	Somatic cell DNA recombination →	+0.085	+2.181	<.001	.001	3	9
SKIN	Somatic diversification of immune receptors via germline recombination within a single locus →	+0.085	+2.181	<.001	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Glycine decarboxylation via glycine cleavage system →	+0.278	+0.866	.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Glycine catabolic process →	+0.278	+0.866	.001	.002	3	9
BLOOD_Leukemia	Nucleoside monophosphate biosynthetic process →	+0.090	+1.320	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,153 associations by consensus.

Response to thyroxine by PRDX1 expression — OESOPHAGUS

Explore this box plot interactively →