PRDX1

Across TCGA cell cohorts, PRDX1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,313 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PRDX1-associated genes across cancer lineages are AKR1A1, GSR, and PGD. Each is linked with PRDX1 in more than 8 cancer types. Because this analysis shows association rather than direction, both PRDX1-to-partner and partner-to-PRDX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDX1 versus AKR1A1 in BLOOD_Leukemia, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDX1→partner) and Y-score (partner→PRDX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	AKR1A1 →	+1.020	+1.364	<.001	<.001	3	9
LARGE_INTESTINE	GSR →	+1.378	+2.019	<.001	.003	3	8
UPPER_AERODIGESTIVE_TRACT	PGD →	+1.662	+2.107	<.001	<.001	3	7
LUNG_SCLC	RPS2 →	+1.247	+1.305	<.001	<.001	3	7
STOMACH	UQCRH →	+1.210	+2.131	.001	<.001	3	7
BLOOD_Myeloma	NASP →	+1.372	+1.599	.005	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,313 associations by consensus.

PRDX1 vs AKR1A1 — BLOOD_Leukemia

Explore this scatter interactively →