PRDM5

Across TCGA patient cohorts, PRDM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,175 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PRDM5-associated proteins across cancer lineages are PRKG1, TLN2, and TNS1. Each is linked with PRDM5 in more than 6 cancer types. Because this analysis shows association rather than direction, both PRDM5-to-partner and partner-to-PRDM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM5 versus PRKG1 in UCEC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM5→partner) and Y-score (partner→PRDM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRKG1 →	+0.648	+0.830	.001	<.001	3	6
BRCA	TLN2 →	+0.560	+0.618	<.001	<.001	3	6
UCEC	TNS1 →	+0.607	+0.722	.001	.002	3	6
UCEC	SORBS3 →	+0.490	+0.706	.001	.002	3	6
BRCA	UTRN →	+0.300	+0.492	<.001	<.001	3	6
UCEC	KANK2 →	+0.529	+0.746	.004	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,175 associations by consensus.

PRDM5 vs PRKG1 — UCEC

Explore this scatter interactively →