PRDM5

Across TCGA patient cohorts, PRDM5 protein abundance is significantly associated with the RNA expression of many other genes, with 1,976 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRDM5-associated genes across cancer lineages are SH2D4A, CD37, and FOXJ1. Each is linked with PRDM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRDM5-to-partner and partner-to-PRDM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM5 versus SH2D4A in PDAC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM5→partner) and Y-score (partner→PRDM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SH2D4A →	+0.955	+0.330	.006	.002	2	1
PDAC	CD37 →	+0.359	+0.330	.001	.002	2	1
PDAC	FOXJ1 →	-1.875	-0.330	.005	.002	2	1
PDAC	HID1 →	+1.199	+0.330	.006	.002	2	1
PDAC	GRIK1 →	-0.655	-0.330	.002	.002	2	1
PDAC	PIK3CD →	+0.375	+0.330	<.001	.002	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,976 associations by consensus.

PRDM5 vs SH2D4A — PDAC

Explore this scatter interactively →