PRDM4

Across TCGA cell cohorts, PRDM4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,788 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRDM4-associated GO terms across cancer lineages are Transcription elongation-coupled chromatin remodeling, Positive regulation of pinocytosis, and Positive regulation of organelle assembly. Each is linked with PRDM4 in more than 12 cancer types. Because this analysis shows association rather than direction, both PRDM4-to-partner and partner-to-PRDM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation-coupled chromatin remodeling grouped by PRDM4-low versus PRDM4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM4→partner) and Y-score (partner→PRDM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Transcription elongation-coupled chromatin remodeling →	+0.118	+0.646	<.001	<.001	3	13
LARGE_INTESTINE	Positive regulation of pinocytosis →	+0.129	+0.752	<.001	<.001	3	12
LARGE_INTESTINE	Positive regulation of organelle assembly →	+0.060	+0.634	.001	.001	3	12
LUNG_SCLC	Adiponectin-activated signaling pathway →	+0.110	+0.546	.004	<.001	3	12
KIDNEY	Response to hepatocyte growth factor →	+0.108	+0.743	.005	<.001	3	12
CNS	Protein targeting to vacuole →	+0.078	+0.573	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,788 associations by consensus.

Transcription elongation-coupled chromatin remodeling by PRDM4 expression — BONE

Explore this box plot interactively →