PRDM15

Across TCGA patient cohorts, PRDM15 protein abundance is significantly associated with the RNA expression of many other genes, with 3,964 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRDM15-associated genes across cancer lineages are MIR4322, PAIP2B, and NTPCR. Each is linked with PRDM15 in more than 1 cancer types. Because this analysis shows association rather than direction, both PRDM15-to-partner and partner-to-PRDM15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM15 versus MIR4322 in UCEC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM15→partner) and Y-score (partner→PRDM15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4322 →	+2.291	+0.416	<.001	.004	3	2
OV	PAIP2B →	+1.065	+0.668	.001	.005	3	2
OV	NTPCR →	+0.689	+0.550	<.001	.003	3	2
OV	UNC119B →	+1.028	+0.574	<.001	.002	3	2
OV	RNF227 →	+0.981	+0.553	<.001	<.001	3	2
OV	NELL2 →	+1.123	+0.442	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,964 associations by consensus.

PRDM15 vs MIR4322 — UCEC

Explore this scatter interactively →