PRDM10

Across TCGA patient cohorts, PRDM10 protein abundance is significantly associated with the RNA expression of many other genes, with 9,523 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRDM10-associated genes across cancer lineages are GAS5, ZNF131, and HINFP. Each is linked with PRDM10 in more than 3 cancer types. Because this analysis shows association rather than direction, both PRDM10-to-partner and partner-to-PRDM10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM10 versus GAS5 in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM10→partner) and Y-score (partner→PRDM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GAS5 →	+0.638	+0.206	<.001	<.001	3	4
LSCC	ZNF131 →	+0.488	+0.197	<.001	<.001	3	3
COAD	HINFP →	+0.457	+0.550	.008	.002	3	3
GBM	KRBA2 →	+0.518	+0.230	.002	.007	3	3
COAD	ZFP62 →	+0.526	+0.419	<.001	.002	3	3
COAD	C5orf51 →	+0.546	+0.477	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,523 associations by consensus.

PRDM10 vs GAS5 — LSCC

Explore this scatter interactively →