PRDM10

Across TCGA cell cohorts, PRDM10 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,042 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PRDM10-associated GO terms across cancer lineages are Regulation of double-strand break repair via homologous recombination, Regulation of double-strand break repair, and Epigenetic regulation of gene expression. Each is linked with PRDM10 in more than 16 cancer types. Because this analysis shows association rather than direction, both PRDM10-to-partner and partner-to-PRDM10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via homologous recombination grouped by PRDM10-low versus PRDM10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM10→partner) and Y-score (partner→PRDM10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of double-strand break repair via homologous recombination →	+0.132	+0.814	<.001	.001	3	17
BONE	Regulation of double-strand break repair →	+0.078	+0.659	<.001	.001	3	17
BONE	Epigenetic regulation of gene expression →	+0.107	+1.073	<.001	<.001	3	17
SOFT_TISSUE	Nucleocytoplasmic transport →	+0.066	+0.472	<.001	<.001	3	17
BONE	Nuclear export →	+0.121	+0.839	<.001	<.001	3	17
STOMACH	Positive regulation of double-strand break repair →	+0.099	+0.814	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,042 associations by consensus.

Regulation of double-strand break repair via homologous recombination by PRDM10 expression — BONE

Explore this box plot interactively →