PRDM1

Across TCGA patient cohorts, PRDM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,238 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PRDM1-associated proteins across cancer lineages are WIPF1, SERPINB9, and LCP2. Each is linked with PRDM1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PRDM1-to-partner and partner-to-PRDM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRDM1 versus WIPF1 in OV, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRDM1→partner) and Y-score (partner→PRDM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WIPF1 →	+0.426	+0.763	<.001	<.001	3	8
UCEC	SERPINB9 →	+0.717	+1.157	<.001	<.001	3	8
BRCA	LCP2 →	+0.619	+0.843	<.001	<.001	3	8
LSCC	ENTPD1 →	+0.568	+0.867	<.001	<.001	3	8
OV	ICAM3 →	+0.607	+0.963	.002	.004	3	7
OV	IGKV3-20 →	+1.286	+1.123	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,238 associations by consensus.

PRDM1 vs WIPF1 — OV

Explore this scatter interactively →