PRCP

Across TCGA pan-cancer cohorts, PRCP mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated PRCP data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PRCP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated PRCP expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, HNSC, and CCRCC are the cancer types where PRCP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.738	0.282	<.001	35	view →
HNSC	OS	Tertile	All	0.941	1.000	.019	5	view →
CCRCC	OS	Quartile	II,III,IV	0.813	1.000	.033	3	view →
LSCC	DFS	Quartile	III,IV	0.278	0.773	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

PRCP–LUAD (DFS)

Open the LUAD breakdown →