PRCP

Across TCGA patient cohorts, PRCP mutation is significantly associated with the RNA expression of many other genes, with 643 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PRCP-associated genes across cancer lineages are OR10G6, RN7SL303P, and MTCO2P32. Each is linked with PRCP in more than 1 cancer types. Because this analysis shows association rather than direction, both PRCP-to-partner and partner-to-PRCP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G6 grouped by PRCP-low versus PRCP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PRCP→partner) and Y-score (partner→PRCP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR10G6 →	+0.257	+4.893	<.001	.005	3	2
COAD	RN7SL303P →	+0.671	+4.602	<.001	.008	3	2
COAD	MTCO2P32 →	+0.492	+5.392	<.001	.002	3	2
UCEC	RNU4-65P →	+0.166	+3.231	<.001	.004	3	2
LUSC	RN7SL332P →	+0.329	+4.882	<.001	.005	3	2
LIHC	MIR6760 →	+0.729	+5.268	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 643 associations by consensus.

OR10G6 by PRCP expression — COAD

Explore this box plot interactively →