PRCC

Across TCGA cell cohorts, PRCC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,043 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PRCC-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Positive regulation of double-strand break repair via homologous recombination, and Regulation of DNA repair. Each is linked with PRCC in more than 15 cancer types. Because this analysis shows association rather than direction, both PRCC-to-partner and partner-to-PRCC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by PRCC-low versus PRCC-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRCC→partner) and Y-score (partner→PRCC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Epigenetic regulation of gene expression →	+0.067	+0.741	.008	.001	3	16
STOMACH	Positive regulation of double-strand break repair via homologous recombination →	+0.089	+0.661	<.001	.001	3	15
BONE	Regulation of DNA repair →	+0.086	+0.839	.001	<.001	3	14
STOMACH	Heterochromatin organization →	+0.065	+0.627	.003	.001	3	14
LIVER	Regulation of protein sumoylation →	+0.153	+0.702	<.001	.004	3	14
BONE	Regulation of double-strand break repair via homologous recombination →	+0.113	+0.820	.004	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,043 associations by consensus.

Epigenetic regulation of gene expression by PRCC expression — STOMACH

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