Across TCGA cell cohorts, PRC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,531 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PRC1-associated GO terms across cancer lineages are Chromosome condensation, Chromosome localization, and Chromosome segregation. Each is linked with PRC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both PRC1-to-partner and partner-to-PRC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PRC1→partner) and Y-score (partner→PRC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Chromosome condensation →	+0.188	+1.153	<.001	<.001	3	20
KIDNEY	Chromosome localization →	+0.112	+1.228	<.001	<.001	3	20
OESOPHAGUS	Chromosome segregation →	+0.152	+1.279	.001	.006	3	20
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.112	+1.464	<.001	<.001	3	19
OESOPHAGUS	Negative regulation of cell cycle process →	+0.097	+1.335	.001	.006	3	19
OESOPHAGUS	Mitotic nuclear division →	+0.150	+1.263	.003	.007	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,531 associations by consensus.

Exploration

PRC1 survival (RNA) · tumor vs normal (RNA) · all PRC1 data types