PRC1-AS1

Across TCGA pan-cancer cohorts, PRC1-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PRC1-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher PRC1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PRC1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LUSC show a favorable association.

KICH, UCS, and LUSC are the cancer types where PRC1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	III,IV	0.240	1.000	.001	85	view →
UCS	DFS	Median	II,III,IV	0.631	0.242	<.001	74	view →
LUSC	OS	Tertile	II,III,IV	0.820	0.624	.001	54	view →
LIHC	DFS	Quartile	All	0.431	0.631	<.001	49	view →
READ	OS	Median	II,III,IV	0.803	0.481	.001	39	view →
KIRC	DFS	Tertile	II,III,IV	0.380	0.598	.004	27	view →
STAD	OS	Median	III,IV	0.666	0.344	.010	24	view →
KIRP	DFS	Median	All	0.361	0.691	.002	22	view →
THYM	DFS	Tertile	All	1.000	0.829	.012	18	view →
LGG	OS	Median	All	0.947	0.840	<.001	18	view →
SKCM	DFS	Quartile	All	0.670	0.540	.007	11	view →
BLCA	OS	Tertile	II,III,IV	0.518	0.261	.016	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PRC1-AS1–KICH (DFS)

Open the KICH breakdown →